COGNAC users have the choice of providing three types of input for searching:
Please select one of the search options below:
: Allows a user to search a database of PDB sourced structures for hydrogen bonded base interactions from base pairs to formations containing as many as six bases.
Search RNA Structures in the PDB
: A user with an RNA structure of interest can opt to upload the structure and then annotate the structure for all possible hydrogen bonded base interactions.
Upload a RNA Structure (PDB file):
: A user can opt to compare the COGNAC hydrogen bonded interactions annotations for two different but closely related structures - such as between mutants or structures that are bound and unbound to ligands.
Compare hits for two RNA Structures
If you choose to upload your own structure, it may take some time until the next frame appears.